HCM Risk-SCD

HCM Risk-SCD is a risk calculator for sudden cardiac death in patients with hypertrophic cardiomyopathy recommended by the European Society of Cardiology. It is based on the publication O'Mahony C, Jichi F, Pavlou M, et al. A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (Hcm risk-scd). European Heart Journal. 2014;35(30):2010-2020


The calculator is intended for patients over 16 years of age and should not be used in elite athletes, patients with Fabry disease or Noonan syndrome. The resulting 5-year risk of sudden cardiac death can be used to decide whether to implant an implantable cardioverter-defibrillator (ICD) in a patient with hypertrophic cardiomyopathy.


Five-year risk below 4% is considered low and ICD implantation is not necessary. Exceptions are the presence of any of the clinical factors such as the presence of scar on MRI (late myocardial saturation of more than 15%) or a reduced left ventricular ejection fraction below 50%. At five-year risk 4-6% ICD implantation may be considered, but the evidence for benefit is not very strong. At 5-year risk above 6% then ICD implantation should always be considered and the evidence of benefit is quite strong.


The main risk factors for sudden cardiac death in patients with hypertrophic cardiomyopathy on which the HCM Risk-SCD calculator recommended by the European Society of Cardiology is based.

Major risk factors for sudden cardiac death in patients with hypertrophic cardiomyopathy.

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